Depression can be a crippling disease that affects people in many ways. For entrepreneurs, it can be difficult to cope with the stress and demands of starting and running a business. These depression quotes compiled by entrepreneur.com offer some words of wisdom and hope for anyone struggling with this condition.

1. When I graduated from high school, it was during the Depression and we had no money. — Ray Bradbury
2. Avoiding depression with large daily doses of television. — Paulo Coelho
3. I’ve struggled with depression before. For me, music was always a very positive way to will myself out of that situation. — Washed Out
4. My films are therapy for my debilitating depression. In institutions people weave baskets. I make films. — Woody Allen
5. Idealism + Inaction = Depression — Oli Anderson, Personal Revolutions: A Short Course in Realness
6. While I don’t equate the dark night with depression, I do think our depressive moods could be imagined spiritually rather than only psychologically. — San Juan de la Cruz
7. Everything I learned about the Great Depression was from a college textbook. — Ralph Abernathy
8. To evade insanity and depression, we unconsciously limit the number of people toward whom we are sincerely sympathetic. — Mokokoma Mokhonoana
9. Sadness is a moment in which the world took something from you. Depression is a lifetime of torment no matter what is said or done. — A.P. Sweet, dead, but dreaming
10. Depression’s a mood killer. People crowding you, asking if you’re okay. Deperssion; the world’s worst thing. — TheKatAttack
11. If our minds can hold us back, then they can push us forwards too. — Sally Brampton, Shoot the Damn Dog: A Memoir of Depression
12. I’ve always been interested in the Depression as this very dramatic pivotal period in American history. — Ron Howard
13. Depression is not generalized pessimism, but pessimism specific to the effects of one’s own skilled action. — Robert M. Sapolsky, Why Zebras Don’t Get Ulcers
14. Letting go is not getting rid of. Letting go is letting be. — Sally Brampton, Shoot the Damn Dog: A Memoir of Depression
15. Before you diagnose yourself with depression or low self–esteem, first make sure that you are not, in fact, just surrounded by assholes. — William Gibson
16. Mental health can be just as important as physical health–and major depression is one of the most commonly diagnosed mental illnesses. — Michael Greger
17. It’s a recession when your neighbor loses his job — it’s a depression when you lose your own.
18. Aggression, Violence, Exploitation, Depression, Despair, Prejudice, War, Intolerance, Poverty, Are all a result of a misunderstanding of the nature of Self. — Shoryu Bradley
19. Dealing with depression isn’t about trying to run away from the feeling — it’s about learning to walk alongside it.
20. The ascetic remembrance of death is opposed to akedia, to anxiety, to depression, and becomes a powerful reminder of eternity, its joyful nostalgia. — Paul Evdokimov, Orthodoxy
21. The best advice is to get on with it. I’m very prone to falling into depressions–not clinical, just ‘can’t be bothered.’ It’s such a waste of time. — Peter Capaldi
22. Depression is not an absence of happiness, it’s a feeling that happiness may never return. — Steven Aitchison
23. If our minds can hold us back, then they can push us forwards too. — Sally Brampton, Shoot the Damn Dog: A Memoir of Depression
24. Bouncing on beds, I remember from childhood, is a great depression reliever. — Robert M. Pirsig, Zen and the Art of Motorcycle Maintenance: An Inquiry Into Values
25. Depression is an illness that robs one of the meaning of life. Heal the illness. As the depression heals, enthusiasm, well–being, and a sense of life’s purpose will return. — Peter Mcwilliams
26. I thought by masking the depression with silence, the feelings might disappear. — Sharon E. Rainey, Making a Pearl from the Grit of Life
27. He didn’t understand depression. To him it was weakness. — Mitch Albom
28. One thing I know is true. Try never to abandon hope for if you do, hope will surely try to abandon you. — Sally Brampton, Shoot the Damn Dog: A Memoir of Depression
29. Depression is our way of telling ourselves that something is seriously wrong and needs working through and changing. — Neel Burton, Heaven and Hell: The Psychology of the Emotions
30. A recession is when your neighbor loses his job. A depression is when you lose yours. — Ronald Reagan
31. Work and learn in evil days, in insulted days, in days of debt and depression and calamity. Fight best in the shade of the cloud of arrows. — Ralph Waldo Emerson
32. If you look at suicides, most of them are connected to depression. And the mental health system just fails them. It’s so sad. We know what to do. We just don’t do it. — Rosalynn Carter
33. I love new clothes. If everyone could just wear new clothes everyday, I reckon depression wouldn’t exist anymore. — Sophie Kinsella, Confessions of a Shopaholic
34. Aggression, Violence, Exploitation, Depression, Despair, Prejudice, War, Intolerance, Poverty, Are all a result of a misunderstanding of the nature of Self. — Shoryu Bradley
35. If you look at suicides, most of them are connected to depression. And the mental health system just fails them. It’s so sad. We know what to do. We just don’t do it. — Rosalynn Carter
36. Mental health can be just as important as physical health–and major depression is one of the most commonly diagnosed mental illnesses. — Michael Greger
37. Rebukeobstinate regressionbringing untold pathsof deep dark forebodingdepression… — Muse, Enigmatic Evolution
38. The feelings of guilt takes away self–confidence, reduces self–esteem welcomes fear, confusion, disappointment, depression etc. — Sunday Adelaja
39. Depression: the healthy suspicion that modern life has no meaning and that modern society is absurd and alienating. — Neel Burton, The Meaning of Madness
40. It’s really easy to slide into a depression fueled by the pointlessness of existence. — Robert Smith
41. I didn’t feel the Depression at all. I always had a pocketful of money. — Walter Annenberg
42. Poverty, oppression, grief and depression will increase, if a country does not live according to the rules of God. — Sunday Adelaja
43. It is a fact that one man can be deliriously happy in the exact situation that causes another man to wither from depression. — Richelle E. Goodrich, Making Wishes
44. I’d like to see a slasher movie set in the depression. — Robert Englund
45. The periods of unemployment accompanying depression in the business cycle . . . present a challenge to all our claims to progress, humanity, and civilization. — Samuel Gompers
46. I believe, completely, that life is about connection; that nothing else truly matters. — Sally Brampton, Shoot the Damn Dog: A Memoir of Depression
47. I’d like to see a slasher movie set in the depression. — Robert Englund
48. Music can lift us out of depression or move us to tears–it is a remedy, a tonic, orange juice for the ear. — Oliver Sacks
49. Oddly enough I never used to suffer from depression on cold, gray, cloudy days like this. I feel as if nature is in harmony with me, that it reflected my soul. — Paulo Coelho
50. Depression isn’t about, ‘Woe is me, my life is this, that and the other’, it’s like having the worst flu all day that you just can’t kick. — Robbie Williams